The information highlighted (if any) are the most recent updates for this brand.
Hypersensitivity to active ingredients linagliptin and/or metformin hydrochloride or to any of the excipients; Any type of acute metabolic acidosis (such as lactic acidosis, diabetic ketoacidosis); Diabetic pre-coma; Severe renal failure (CrCl <30mL/min or eGFR <30 mL/min/1.73m2); Acute conditions with the potential to alter renal function such as: dehydration, severe infection, shock, intravascular administration of iodinated contrast agents (see Precautions); Disease which may cause tissue hypoxia (especially acute disease, or worsening of chronic disease) such as: decompensated heart failure, respiratory failure, recent myocardial infarction, shock; Hepatic impairment; Acute alcohol intoxication; Alcoholism.
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